Durham, North Carolina to Pittsburgh: Road Trip Guide & Distance

How far is Durham, North Carolina from Pittsburgh?

The distance from Durham, North Carolina to Pittsburgh is 312.9 miles (503.6 km) as the crow flies. Pittsburgh is located N of Durham, North Carolina. By car, the driving distance is approximately 375.5 miles, taking about 7h 33min. A direct flight would take roughly 1h 8min. Both are located in United States — Durham, North Carolina in North Carolina and Pittsburgh in Pennsylvania.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time.

Coordinates come from public place data for Durham, North Carolina and Pittsburgh. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.