Dubuque to Saint Charles, Missouri: Road Trip Guide & Distance

How far is Dubuque from Saint Charles, Missouri?

The distance from Dubuque to Saint Charles, Missouri is 257 miles (413.6 km) as the crow flies. Saint Charles, Missouri is located S of Dubuque. By car, the driving distance is approximately 321.2 miles, taking about 6h 28min. A direct flight would take roughly 1h 1min. Both are located in United States — Dubuque in Iowa and Saint Charles, Missouri in Missouri.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee.

Coordinates come from public place data for Dubuque and Saint Charles, Missouri. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.