Dothan to Port Saint Lucie: Road Trip Guide & Distance

How far is Dothan from Port Saint Lucie?

The distance from Dothan to Port Saint Lucie is 407.3 miles (655.5 km) as the crow flies. Port Saint Lucie is located SE of Dothan. By car, the driving distance is approximately 488.8 miles, taking about 9h 50min. A direct flight would take roughly 1h 19min. Both are located in United States — Dothan in Alabama and Port Saint Lucie in Florida.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Dothan and Port Saint Lucie. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.