Des Moines to Syracuse, New York: Road Trip Guide & Distance

How far is Des Moines from Syracuse, New York?

The distance from Des Moines to Syracuse, New York is 896.9 miles (1443.5 km) as the crow flies. Syracuse, New York is located ENE of Des Moines. By car, the driving distance is approximately 1076.3 miles, taking about 21h 39min. A direct flight would take roughly 2h 18min. Both are located in United States — Des Moines in Iowa and Syracuse, New York in New York.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Des Moines and Syracuse, New York. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.