Des Moines to San Antonio: Road Trip Guide & Distance

How far is Des Moines from San Antonio?

The distance from Des Moines to San Antonio is 883.5 miles (1421.8 km) as the crow flies. San Antonio is located SSW of Des Moines. By car, the driving distance is approximately 1005.9 miles, taking about 17h 39min. A direct flight would take roughly 2h 17min. Both are located in United States — Des Moines in Iowa and San Antonio in Texas.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Des Moines and San Antonio. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.