Des Moines to Mesa: Road Trip Guide & Distance

How far is Des Moines from Mesa?

The distance from Des Moines to Mesa is 1143.2 miles (1839.8 km) as the crow flies. Mesa is located WSW of Des Moines. By car, the driving distance is approximately 1386.4 miles, taking about 25h 33min. A direct flight would take roughly 2h 48min. Both are located in United States — Des Moines in Iowa and Mesa in Arizona.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Des Moines and Mesa. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.