Des Moines to Jacksonville, Illinois: Road Trip Guide & Distance

How far is Des Moines from Jacksonville, Illinois?

The distance from Des Moines to Jacksonville, Illinois is 219.2 miles (352.8 km) as the crow flies. Jacksonville, Illinois is located SE of Des Moines. By car, the driving distance is approximately 274 miles, taking about 5h 31min. A direct flight would take roughly 56min. Both are located in United States — Des Moines in Iowa and Jacksonville, Illinois in Illinois.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Des Moines and Jacksonville, Illinois. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.