Des Moines to Gillette: Road Trip Guide & Distance

How far is Des Moines from Gillette?

The distance from Des Moines to Gillette is 628.5 miles (1011.5 km) as the crow flies. Gillette is located WNW of Des Moines. By car, the driving distance is approximately 754.2 miles, taking about 15h 10min. A direct flight would take roughly 1h 46min. Both are located in United States — Des Moines in Iowa and Gillette in Wyoming.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Des Moines and Gillette. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.