Danville, Illinois to Tupelo: Road Trip Guide & Distance

How far is Danville, Illinois from Tupelo?

The distance from Danville, Illinois to Tupelo is 409.6 miles (659.2 km) as the crow flies. Tupelo is located S of Danville, Illinois. By car, the driving distance is approximately 491.5 miles, taking about 9h 53min. A direct flight would take roughly 1h 19min. Both are located in United States — Danville, Illinois in Illinois and Tupelo in Mississippi.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. As you head South, expect warmer temperatures. Make sure your car's AC is working well before embarking on this journey.

Coordinates come from public place data for Danville, Illinois and Tupelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.