Danville, Illinois to Kirksville: Road Trip Guide & Distance

How far is Danville, Illinois from Kirksville?

The distance from Danville, Illinois to Kirksville is 261.6 miles (421 km) as the crow flies. Kirksville is located W of Danville, Illinois. By car, the driving distance is approximately 327 miles, taking about 6h 35min. A direct flight would take roughly 1h 2min. Both are located in United States — Danville, Illinois in Illinois and Kirksville in Missouri.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Danville, Illinois and Kirksville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.