Cypress to Tupelo: Road Trip Guide & Distance

How far is Cypress from Tupelo?

The distance from Cypress to Tupelo is 505.1 miles (812.8 km) as the crow flies. Tupelo is located NE of Cypress. By car, the driving distance is approximately 606.1 miles, taking about 12h 12min. A direct flight would take roughly 1h 31min. Both are located in United States — Cypress in Texas and Tupelo in Mississippi.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Cypress and Tupelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.