Columbus, Indiana to Jackson, Mississippi: Road Trip Guide & Distance

How far is Columbus, Indiana from Jackson, Mississippi?

The distance from Columbus, Indiana to Jackson, Mississippi is 533.3 miles (858.3 km) as the crow flies. Jackson, Mississippi is located SSW of Columbus, Indiana. By car, the driving distance is approximately 640 miles, taking about 12h 53min. A direct flight would take roughly 1h 34min. Both are located in United States — Columbus, Indiana in Indiana and Jackson, Mississippi in Mississippi.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Columbus, Indiana and Jackson, Mississippi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.