Columbia, Tennessee to Greenville, South Carolina: Road Trip Guide & Distance

How far is Columbia, Tennessee from Greenville, South Carolina?

The distance from Columbia, Tennessee to Greenville, South Carolina is 267.1 miles (429.9 km) as the crow flies. Greenville, South Carolina is located E of Columbia, Tennessee. By car, the driving distance is approximately 333.9 miles, taking about 6h 43min. A direct flight would take roughly 1h 2min. Both are located in United States — Columbia, Tennessee in Tennessee and Greenville, South Carolina in South Carolina.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Columbia, Tennessee and Greenville, South Carolina. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.