Columbia, South Carolina to Lafayette, Indiana: Road Trip Guide & Distance

How far is Columbia, South Carolina from Lafayette, Indiana?

The distance from Columbia, South Carolina to Lafayette, Indiana is 547.2 miles (880.7 km) as the crow flies. Lafayette, Indiana is located NW of Columbia, South Carolina. By car, the driving distance is approximately 656.7 miles, taking about 13h 13min. A direct flight would take roughly 1h 36min. Both are located in United States — Columbia, South Carolina in South Carolina and Lafayette, Indiana in Indiana.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Columbia, South Carolina and Lafayette, Indiana. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.