Columbia, South Carolina to Jackson, Mississippi: Road Trip Guide & Distance

How far is Columbia, South Carolina from Jackson, Mississippi?

The distance from Columbia, South Carolina to Jackson, Mississippi is 542 miles (872.3 km) as the crow flies. Jackson, Mississippi is located W of Columbia, South Carolina. By car, the driving distance is approximately 650.5 miles, taking about 13h 5min. A direct flight would take roughly 1h 35min. Both are located in United States — Columbia, South Carolina in South Carolina and Jackson, Mississippi in Mississippi.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Columbia, South Carolina and Jackson, Mississippi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.