Columbia, Missouri to Lexington, Kentucky: Road Trip Guide & Distance

How far is Columbia, Missouri from Lexington, Kentucky?

The distance from Columbia, Missouri to Lexington, Kentucky is 427.9 miles (688.7 km) as the crow flies. Lexington, Kentucky is located E of Columbia, Missouri. By car, the driving distance is approximately 513.5 miles, taking about 10h 20min. A direct flight would take roughly 1h 22min. Both are located in United States — Columbia, Missouri in Missouri and Lexington, Kentucky in Kentucky.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Columbia, Missouri and Lexington, Kentucky. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.