Columbia, Missouri to Lafayette, Indiana: Road Trip Guide & Distance

How far is Columbia, Missouri from Lafayette, Indiana?

The distance from Columbia, Missouri to Lafayette, Indiana is 307.3 miles (494.6 km) as the crow flies. Lafayette, Indiana is located ENE of Columbia, Missouri. By car, the driving distance is approximately 384.2 miles, taking about 7h 44min. A direct flight would take roughly 1h 7min. Both are located in United States — Columbia, Missouri in Missouri and Lafayette, Indiana in Indiana.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Columbia, Missouri and Lafayette, Indiana. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.