Clinton, Iowa to Sioux Falls: Road Trip Guide & Distance

How far is Clinton, Iowa from Sioux Falls?

The distance from Clinton, Iowa to Sioux Falls is 352.1 miles (566.7 km) as the crow flies. Sioux Falls is located WNW of Clinton, Iowa. By car, the driving distance is approximately 422.5 miles, taking about 8h 30min. A direct flight would take roughly 1h 13min. Both are located in United States — Clinton, Iowa in Iowa and Sioux Falls in South Dakota.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Clinton, Iowa and Sioux Falls. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.