Clarksville to Greenville, Mississippi: Road Trip Guide & Distance

How far is Clarksville from Greenville, Mississippi?

The distance from Clarksville to Greenville, Mississippi is 300.6 miles (483.8 km) as the crow flies. Greenville, Mississippi is located SW of Clarksville. By car, the driving distance is approximately 375.8 miles, taking about 7h 34min. A direct flight would take roughly 1h 6min. Both are located in United States — Clarksville in Tennessee and Greenville, Mississippi in Mississippi.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Clarksville and Greenville, Mississippi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.