Clarksdale to Madison, Alabama: Road Trip Guide & Distance

How far is Clarksdale from Madison, Alabama?

The distance from Clarksdale to Madison, Alabama is 220.5 miles (354.9 km) as the crow flies. Madison, Alabama is located E of Clarksdale. By car, the driving distance is approximately 275.6 miles, taking about 5h 33min. A direct flight would take roughly 57min. Both are located in United States — Clarksdale in Mississippi and Madison, Alabama in Alabama.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Clarksdale and Madison, Alabama. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.