Cincinnati to Lancaster, Pennsylvania: Road Trip Guide & Distance

How far is Cincinnati from Lancaster, Pennsylvania?

The distance from Cincinnati to Lancaster, Pennsylvania is 441.7 miles (710.8 km) as the crow flies. Lancaster, Pennsylvania is located E of Cincinnati. By car, the driving distance is approximately 530 miles, taking about 10h 40min. A direct flight would take roughly 1h 23min. Both are located in United States — Cincinnati in Ohio and Lancaster, Pennsylvania in Pennsylvania.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Cincinnati and Lancaster, Pennsylvania. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.