Chillicothe to Smyrna: Road Trip Guide & Distance

How far is Chillicothe from Smyrna?

The distance from Chillicothe to Smyrna is 301.6 miles (485.4 km) as the crow flies. Smyrna is located SW of Chillicothe. By car, the driving distance is approximately 377 miles, taking about 7h 35min. A direct flight would take roughly 1h 6min. Both are located in United States — Chillicothe in Ohio and Smyrna in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Chillicothe and Smyrna. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.