Chillicothe to Roanoke: Road Trip Guide & Distance

How far is Chillicothe from Roanoke?

The distance from Chillicothe to Roanoke is 217.9 miles (350.7 km) as the crow flies. Roanoke is located SE of Chillicothe. By car, the driving distance is approximately 272.4 miles, taking about 5h 29min. A direct flight would take roughly 56min. Both are located in United States — Chillicothe in Ohio and Roanoke in Virginia.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Chillicothe and Roanoke. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.