Chillicothe to Madison, Alabama: Road Trip Guide & Distance

How far is Chillicothe from Madison, Alabama?

The distance from Chillicothe to Madison, Alabama is 381.6 miles (614.1 km) as the crow flies. Madison, Alabama is located SW of Chillicothe. By car, the driving distance is approximately 457.9 miles, taking about 9h 13min. A direct flight would take roughly 1h 16min. Both are located in United States — Chillicothe in Ohio and Madison, Alabama in Alabama.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Chillicothe and Madison, Alabama. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.