Charleston, South Carolina to Greenville, North Carolina: Road Trip Guide & Distance

How far is Charleston, South Carolina from Greenville, North Carolina?

The distance from Charleston, South Carolina to Greenville, North Carolina is 244.7 miles (393.8 km) as the crow flies. Greenville, North Carolina is located NE of Charleston, South Carolina. By car, the driving distance is approximately 305.9 miles, taking about 6h 9min. A direct flight would take roughly 1h 0min. Both are located in United States — Charleston, South Carolina in South Carolina and Greenville, North Carolina in North Carolina.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Charleston, South Carolina and Greenville, North Carolina. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.