Charleston, South Carolina to Fort Pierce: Road Trip Guide & Distance

How far is Charleston, South Carolina from Fort Pierce?

The distance from Charleston, South Carolina to Fort Pierce is 369 miles (593.9 km) as the crow flies. Fort Pierce is located S of Charleston, South Carolina. By car, the driving distance is approximately 442.9 miles, taking about 8h 55min. A direct flight would take roughly 1h 15min. Both are located in United States — Charleston, South Carolina in South Carolina and Fort Pierce in Florida.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. As you head South, expect warmer temperatures. Make sure your car's AC is working well before embarking on this journey.

Coordinates come from public place data for Charleston, South Carolina and Fort Pierce. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.