Carlisle, Pennsylvania to Ithaca: Road Trip Guide & Distance

How far is Carlisle, Pennsylvania from Ithaca?

The distance from Carlisle, Pennsylvania to Ithaca is 159 miles (255.9 km) as the crow flies. Ithaca is located NNE of Carlisle, Pennsylvania. By car, the driving distance is approximately 198.8 miles, taking about 4h 0min. A direct flight would take roughly 49min. Both are located in United States — Carlisle, Pennsylvania in Pennsylvania and Ithaca in New York.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. Given the short distance, driving or taking a train is often faster and more convenient than dealing with airport security and flight boarding times.

Coordinates come from public place data for Carlisle, Pennsylvania and Ithaca. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.