Cape Girardeau to Oxford, Mississippi: Road Trip Guide & Distance

How far is Cape Girardeau from Oxford, Mississippi?

The distance from Cape Girardeau to Oxford, Mississippi is 203.1 miles (326.8 km) as the crow flies. Oxford, Mississippi is located S of Cape Girardeau. By car, the driving distance is approximately 253.8 miles, taking about 5h 6min. A direct flight would take roughly 55min. Both are located in United States — Cape Girardeau in Missouri and Oxford, Mississippi in Mississippi.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee.

Coordinates come from public place data for Cape Girardeau and Oxford, Mississippi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.