Cape Girardeau to Huntsville, Alabama: Road Trip Guide & Distance

How far is Cape Girardeau from Huntsville, Alabama?

The distance from Cape Girardeau to Huntsville, Alabama is 241.9 miles (389.3 km) as the crow flies. Huntsville, Alabama is located SE of Cape Girardeau. By car, the driving distance is approximately 302.4 miles, taking about 6h 5min. A direct flight would take roughly 59min. Both are located in United States — Cape Girardeau in Missouri and Huntsville, Alabama in Alabama.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Cape Girardeau and Huntsville, Alabama. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.