Canton, Ohio to Knoxville: Road Trip Guide & Distance

How far is Canton, Ohio from Knoxville?

The distance from Canton, Ohio to Knoxville is 361.5 miles (581.8 km) as the crow flies. Knoxville is located SSW of Canton, Ohio. By car, the driving distance is approximately 433.8 miles, taking about 8h 44min. A direct flight would take roughly 1h 14min. Both are located in United States — Canton, Ohio in Ohio and Knoxville in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Canton, Ohio and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.