Biloxi to Wesley Chapel: Road Trip Guide & Distance

How far is Biloxi from Wesley Chapel?

The distance from Biloxi to Wesley Chapel is 422.1 miles (679.3 km) as the crow flies. Wesley Chapel is located ESE of Biloxi. By car, the driving distance is approximately 506.5 miles, taking about 10h 11min. A direct flight would take roughly 1h 21min. Both are located in United States — Biloxi in Mississippi and Wesley Chapel in Florida.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Biloxi and Wesley Chapel. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.