Biloxi to Opelousas: Road Trip Guide & Distance

How far is Biloxi from Opelousas?

The distance from Biloxi to Opelousas is 190.6 miles (306.7 km) as the crow flies. Opelousas is located W of Biloxi. By car, the driving distance is approximately 238.2 miles, taking about 4h 48min. A direct flight would take roughly 53min. Both are located in United States — Biloxi in Mississippi and Opelousas in Louisiana.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. Given the short distance, driving or taking a train is often faster and more convenient than dealing with airport security and flight boarding times.

Coordinates come from public place data for Biloxi and Opelousas. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.