Biloxi to Cancun: Road Trip Guide & Distance

How far is Biloxi from Cancun?

The distance from Biloxi to Cancun is 650.4 miles (1046.7 km) as the crow flies. Cancun is located SSE of Biloxi. By car, the driving distance is approximately 780.4 miles, taking about 15h 42min. A direct flight would take roughly 1h 49min. Biloxi is in Mississippi, United States, while Cancun is in Mexico.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. Keep in mind this route crosses international borders. Don't forget your passport, and check current border crossing times and vehicle insurance requirements.

Coordinates come from public place data for Biloxi and Cancun. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.