Antioch to Santa Maria: Road Trip Guide & Distance

How far is Antioch from Santa Maria?

The distance from Antioch to Santa Maria is 224.2 miles (360.8 km) as the crow flies. Santa Maria is located SSE of Antioch. By car, the driving distance is approximately 280.2 miles, taking about 5h 38min. A direct flight would take roughly 57min. Both are located in United States.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Antioch and Santa Maria. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.