Anna Maria Island to Biloxi: Road Trip Guide & Distance

How far is Anna Maria Island from Biloxi?

The distance from Anna Maria Island to Biloxi is 421.2 miles (677.9 km) as the crow flies. Biloxi is located WNW of Anna Maria Island. By car, the driving distance is approximately 505.5 miles, taking about 10h 10min. A direct flight would take roughly 1h 21min. Both are located in United States — Anna Maria Island in Florida and Biloxi in Mississippi.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Anna Maria Island and Biloxi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.