Ann Arbor to O'Fallon, Missouri: Road Trip Guide & Distance

How far is Ann Arbor from O'Fallon, Missouri?

The distance from Ann Arbor to O'Fallon, Missouri is 436.7 miles (702.8 km) as the crow flies. O'Fallon, Missouri is located WSW of Ann Arbor. By car, the driving distance is approximately 524.1 miles, taking about 10h 33min. A direct flight would take roughly 1h 23min. Both are located in United States — Ann Arbor in Michigan and O'Fallon, Missouri in Missouri.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Ann Arbor and O'Fallon, Missouri. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.