Ann Arbor to Knoxville: Road Trip Guide & Distance

How far is Ann Arbor from Knoxville?

The distance from Ann Arbor to Knoxville is 436.6 miles (702.6 km) as the crow flies. Knoxville is located S of Ann Arbor. By car, the driving distance is approximately 523.9 miles, taking about 10h 32min. A direct flight would take roughly 1h 23min. Both are located in United States — Ann Arbor in Michigan and Knoxville in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. As you head South, expect warmer temperatures. Make sure your car's AC is working well before embarking on this journey.

Coordinates come from public place data for Ann Arbor and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.