Anderson, South Carolina to Portsmouth, Ohio: Road Trip Guide & Distance

How far is Anderson, South Carolina from Portsmouth, Ohio?

The distance from Anderson, South Carolina to Portsmouth, Ohio is 292.8 miles (471.2 km) as the crow flies. Portsmouth, Ohio is located N of Anderson, South Carolina. By car, the driving distance is approximately 366 miles, taking about 7h 22min. A direct flight would take roughly 1h 5min. Both are located in United States — Anderson, South Carolina in South Carolina and Portsmouth, Ohio in Ohio.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time.

Coordinates come from public place data for Anderson, South Carolina and Portsmouth, Ohio. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.