Anderson, Indiana to Buffalo, New York: Road Trip Guide & Distance

How far is Anderson, Indiana from Buffalo, New York?

The distance from Anderson, Indiana to Buffalo, New York is 400.8 miles (645.1 km) as the crow flies. Buffalo, New York is located ENE of Anderson, Indiana. By car, the driving distance is approximately 481 miles, taking about 9h 41min. A direct flight would take roughly 1h 18min. Both are located in United States — Anderson, Indiana in Indiana and Buffalo, New York in New York.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Anderson, Indiana and Buffalo, New York. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.