Alpharetta to Florence, South Carolina: Road Trip Guide & Distance

How far is Alpharetta from Florence, South Carolina?

The distance from Alpharetta to Florence, South Carolina is 259.2 miles (417.2 km) as the crow flies. Florence, South Carolina is located E of Alpharetta. By car, the driving distance is approximately 324 miles, taking about 6h 31min. A direct flight would take roughly 1h 1min. Both are located in United States — Alpharetta in Georgia and Florence, South Carolina in South Carolina.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Alpharetta and Florence, South Carolina. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.